With the growth of 5G data traffic and AI computing, data centers need faster connectivity to meet the increasing bandwidth. High speed I/O speed beyond 112 Gb/s per lane is required. If we follow the SerDes technology revolution by doubling the data rate per lane in every 2-3 years, the next generation I/O data rate will be 224 Gb/s. In this article, Cathy Liu explores options, technical challenges, and potential solutions to achieve 224 Gb/s per lane.